Main Article Content
Anaemia is a state in which there is a decreased production of red blood cells (RBCs) or a decreased concentration of haemoglobin in the RBCs. This consequently affects RBCs oxygen-carrying capacity to meet the body’s physiologic demands. Globally, iron deficiency is considered to be the most common cause of anaemia but other nutritional deficiencies, acute and chronic inflammation, parasitic infections and inherited or acquired disorders that affect haemoglobin synthesis, red blood cell production or red blood cell survival, can all cause anaemia. Anaemia roughly affects a third of the world’s population out of which half the cases are due to iron deficiency. It is a major and global public health concern that affects maternal and child mortality, physical performance and referral to health-care professionals. Oral iron is readily available, convenient and inexpensive treatment option for anaemia management. Fatigue is considered as the cardinal symptom of anaemia which needs to be addressed along with increasing haemoglobin. This article highlights the roles played by taurine in increasing the effectiveness of oral iron for increasing hemoglobin in iron deficiency anaemia treatment.
Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity; 2011. Accessed 17 August 2020 Available:https://www.who.int/vmnis/indicators/haemoglobin.pdf
WHO Vitamin and Mineral Nutrition Information System (VMNIS); 2008. Accessed 17 August 2020. Available:https://www.who.int/vmnis/anaemia/prevalence/summary/anaemia_data_status_t2/en/
Guidelines for Control of Iron Deficiency Anaemia. Ministry of Health and Family Welfare; 2013. Accessed 17 August 2020. Available: https://www.nhm.gov.in/images/pdf/programmes/child-health/guidelines/Control-of-Iron-Deficiency-Anaemia.pdf
WHO Health Topics Anaemia; 2011. Accessed 17 August 2020. Available: https://www.who.int/health-topics/anaemia#tab=tab_2
Eichner ER. Fatigue of anemia. Nutr Rev. 2001;59(1 Pt 2):S17-S19.
Sobrero A, Puglisi F, Guglielmi A. Fatigue: a main component of anemia symptomatology. Semin Oncol. 2001;28(2 Suppl 8):15-18.
Jimenez K, Kulnigg-Dabsch S, Gasche C. Management of Iron Deficiency Anemia. Gastroenterol Hepatol (N Y). 2015 Apr;11(4):241-50.
DeLoughery TG. Microcytic anemia. N Engl J Med. 2014;371(14):1324- 1331.
Tolkien Z, Stecher L, Mander AP, Pereira DI, Powell JJ. Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: a systematic review and meta- analysis. PLoS One. 2015;10(2): e0117383.
De Luca A, Pierno S, Camerino DC. Taurine: the appeal of a safe amino acid for skeletal muscle disorders. J Transl Med. 2015;13:243.
Higgins JP, Tuttle TD, Higgins CL. Energy beverages: content and safety. Mayo Clin Proc. 2010;85(11):1033-1041.
Sirdah MM, Abushahla AK, Al-Sarraj HA. Effect of the addition of the antioxidant taurine on the complete blood count of whole blood stored at room temperature and at 4ºC for up to 7 days. Rev Bras Hematol Hemoter. 2013;35(1):44-51.
Sirdah MM, El-Agouza IM, Abu Shahla AN. Possible ameliorative effect of taurine in the treatment of iron-deficiency anaemia in female university students of Gaza, Palestine. Eur J Haematol. 2002;69(4): 236-242.
Marcinkiewicz J, Kontny E. Taurine and inflammatory diseases. Amino Acids. 2014;46(1):7-20.